Family-pedigree based mapping

Family based QTL mapping, or Family-pedigree based mapping (Linkage and association mapping), involves multiple families instead of a single family. Family based QTL mapping has been the only way for mapping of genes where experimental crosses are difficult to make. However, due to some advantages, now plant geneticists are attempting to incorporate some of the methods pioneered in human genetics.^[20] Using family-pedigree based approach has been discussed (Bink et al. 2008). Family-based linkage and association has been successfully implemented (Rosyara et al. 2009)^[21]

Francis Galton (cousin of Huxley) – eugenics

Huxleys bulldog
Galton created biometrics

“A pedigree of the Galton–Darwin–Wedgwood families that was exhibited as a poster at the Third International Congress of Eugenics in 1932 at the American Museum of Natural History has been located in the archives of Truman State University in Kirksville, Missouri. This pedigree was prepared by Harry Hamilton Laughlin, Director of the Eugenics Record Office of the Carnegie Institute. The pedigree shows consanguineous marriages within the three families. A special collection of rare Darwin family photographs assembled by Leonard Darwin has also been found in the Truman State University archives. These photographs were exhibited as a poster alongside the pedigree at the 1932 Eugenics Congress. The poster of the Galton–Darwin–Wedgwood pedigree is published here, together with a tabular version providing ready access to the information contained in the pedigree. Also included are the Darwin family photographs and a biographical sketch of Laughlin.” (Berra, et al., 2010; see references below)

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Further References