🗎“Soft robots have opened an emerging research direction in robotics due to their promising performance enabled by functional materials and fabrication technology. recent progress of functional materials has brought soft robots with advanced functionalities and greatly expanded their potential applications in various fields. biomedical applications have attracted significant research interests and become an emerging field. particular trends have been shifted to the submillimeter-scale biomedical soft robots and the integrated manipulatable devices with well controllability and compatibility. functionalities of these biomedical soft robots are dominated by nanomaterials and nanotechnology. however, lack of study has overviewed the promising development progress of functional nanomaterials and advanced nanotechnology in soft robots for biomedical applications. it is worthwhile to review such an important but not yet fully exposed research trend. to address such research gap, this review article focuses on the recent achievements, technological challenges and future trends of the nanomaterials and nanotechnology used in biomedical soft robots. we provide a state-of-the-art review on the current progress while mainly focusing on explaining the mechanism and functionality of the soft robots with respect to the nanomaterials and nanotechnology. in the end, we summarize the main challenges of biomedical soft robots and envision the future trends by outlooking the development of advanced nanomaterials and nanotechnology.”
🗊Liu, K., Chen, W., Yang, W., Jiao, Z., & Yu, Y.. (2023). Review of the Research Progress in Soft Robots. Applied Sciences (Switzerland)
🗎“The soft robot is a new type of robot with strong adaptability, good pliability, and high flexibility. today, it is widely used in the fields of bioengineering, disaster rescue, industrial production, medical services, exploration, and surveying. in this paper, the typical driven methods, 3d printing technologies, applications, the existed problems, and the development prospects for soft robots are summarized comprehensively. firstly, the driven methods and materials of the soft robot are introduced, including fluid driven, smart materials driven, chemical reaction driven, a twisted and coiled polymer actuator, and so on. secondly, the basic principles and characteristics of mainstream 3d printing technologies for soft materials are introduced, including fdm, diw, ip, sla, sls, and so on. then, current applications of soft robots, such as bionic structures, gripping operations, and medical rehabilitation are described. finally, the problems existing in the development of soft robots, such as the shortage of 3d printable soft materials, efficient and effective manufacturing of soft robots, shortage of smart soft materials, efficient use of energy, the realization of complex motion forms of soft robot, control action accuracy and actual kinematic modeling are summarized. based on the above, some suggestions are put forward pertinently, and the future development and applications of the soft robot are prospected.”
🗊Armanini, C., Boyer, F., Mathew, A. T., Duriez, C., & Renda, F.. (2023). Soft Robots Modeling: A Structured Overview. IEEE Transactions on Robotics
🗎“The robotics community has seen an exponential growth in the level of complexity of the theoretical tools presented for the modeling of soft robotics devices. different solutions have been presented to overcome the difficulties related to the modeling of soft robots, often leveraging on other scientific disciplines, such as continuum mechanics, computationalmechanics, and computer graphics. these theoretical and computational foundations are often taken for granted and this leads to an intricate literature that, consequently, has rarely been the subject of a complete review. for the first time, we present here a structured overview of all the approaches proposed so far to model soft robots. the chosen classification, which is based on their theoretical and numerical grounds, allows us to provide a critical analysis about their uses and applicability. this will enable robotics researchers to learn the basics of thesemodeling techniques and their associated numerical methods, but also to have a critical perspective on their uses.”
🗎“The ocean environment has enormous uncertainty due to the influence of complex waves and undercurrents. the human beings are limited in their abilities to detect and utilize marine resources without powerful tools. soft robots employ soft materials to simplify the complex mechanical structures in rigid robots and adapt their morphology to the environment, making them suitable for performing some challenging tasks in place of manual labor. due to superior flexible and deformable bodies, underwater soft robots have played significant roles in numerous applications in recent decades. meanwhile, various technical challenges still need to be tackled to ensure the reliability and practical performance of underwater soft robots in complicated ocean environment. nowadays, some researchers have developed underwater soft robotic systems based on biomimetics and other disciplines, aiming at comprehensive exploration of ocean and appropriate utilization of unexploited resources. this review presents the recent advances of underwater soft robots in the aspects of intelligent soft materials, fabrication, actuation, locomotion patterns, power storage, sensing, control, and modeling; additionally, the existing challenges and perspectives are analyzed as well.”
🗎“Soft robots have received a lot of attention because of their great human-robot interaction and environmental adaptability. most soft robots are currently limited in their applications due to wired drives. photoresponsive soft robotics is one of the most effective ways to promote wireless soft drives. among the many soft robotics materials, photoresponsive hydrogels have received a lot of attention due to their good biocompatibility, ductility, and excellent photoresponse properties. this paper visualizes and analyzes the research hotspots in the field of hydrogels using the literature analysis tool citespace, demonstrating that photoresponsive hydrogel technology is currently a key research direction. therefore, this paper summarizes the current state of research on photoresponsive hydrogels in terms of photochemical and photothermal response mechanisms. the progress of the application of photoresponsive hydrogels in soft robots is highlighted based on bilayer, gradient, orientation, and patterned structures. finally, the main factors influencing its application at this stage are discussed, including the development directions and insights. advancement in photoresponsive hydrogel technology is crucial for its application in the field of soft robotics. the advantages and disadvantages of different preparation methods and structures should be considered in different application scenarios to select the best design scheme.”
🗎“Broad adoption of magnetic soft robotics is hampered by the sophisticated field paradigms for their manipulation and the complexities in controlling multiple devices. furthermore, high-throughput fabrication of such devices across spatial scales remains challenging. here, advances in fiber-based actuators and magnetic elastomer composites are leveraged to create 3d magnetic soft robots controlled by unidirectional fields. thermally drawn elastomeric fibers are instrumented with a magnetic composite synthesized to withstand strains exceeding 600%. a combination of strain and magnetization engineering in these fibers enables programming of 3d robots capable of crawling or walking in magnetic fields orthogonal to the plane of motion. magnetic robots act as cargo carriers, and multiple robots can be controlled simultaneously and in opposing directions using a single stationary electromagnet. the scalable approach to fabrication and control of magnetic soft robots invites their future applications in constrained environments where complex fields cannot be readily deployed.”
🗊Stella, F., & Hughes, J.. (2023). The science of soft robot design: A review of motivations, methods and enabling technologies. Frontiers in Robotics and AI
🗎“Novel technologies, fabrication methods, controllers and computational methods are rapidly advancing the capabilities of soft robotics. this is creating the need for design techniques and methodologies that are suited for the multi-disciplinary nature of soft robotics. these are needed to provide a formalized and scientific approach to design. in this paper, we formalize the scientific questions driving soft robotic design; what motivates the design of soft robots, and what are the fundamental challenges when designing soft robots? we review current methods and approaches to soft robot design including bio-inspired design, computational design and human-driven design, and highlight the implications that each design methods has on the resulting soft robotic systems. to conclude, we provide an analysis of emerging methods which could assist robot design, and we present a review some of the necessary technologies that may enable these approaches.”
🗊Ng, C. S. X., Tan, M. W. M., Xu, C., Yang, Z., Lee, P. S., & Lum, G. Z.. (2021). Locomotion of Miniature Soft Robots. Advanced Materials
🗎“Miniature soft robots are mobile devices, which are made of smart materials that can be actuated by external stimuli to realize their desired functionalities. here, the key advancements and challenges of the locomotion producible by miniature soft robots in micro- to centimeter length scales are highlighted. it is highly desirable to endow these small machines with dexterous locomotive gaits as it enables them to easily access highly confined and enclosed spaces via a noninvasive manner. if miniature soft robots are able to capitalize this unique ability, they will have the potential to transform a vast range of applications, including but not limited to, minimally invasive medical treatments, lab-on-chip applications, and search-and-rescue missions. the gaits of miniature soft robots are categorized into terrestrial, aquatic, and aerial locomotion. except for the centimeter-scale robots that can perform aerial locomotion, the discussions in this report are centered around soft robots that are in the micro- to millimeter length scales. under each category of locomotion, prospective methods and strategies that can improve their gait performances are also discussed. this report provides critical analyses and discussions that can inspire future strategies to make miniature soft robots significantly more agile.”
🗊Kim, J. G., Park, J. E., Won, S., Jeon, J., & Wie, J. J.. (2019). Contactless manipulation of soft robots. Materials
🗎“In recent years, jointless soft robots have demonstrated various curvilinear motions unlike conventional robotic systems requiring complex mechanical joints and electrical design principles. the materials employed to construct soft robots are mainly programmable anisotropic polymeric materials to achieve contactless manipulation of miniaturized and lightweight soft robots through their anisotropic strain responsivity to external stimuli. although reviews on soft actuators are extensive, those on untethered soft robots are scant. in this study, we focus on the recent progress in the manipulation of untethered soft robots upon receiving external stimuli such as magnetic fields, light, humidity, and organic solvents. for each external stimulus, we provide an overview of the working principles along with the characteristics of programmable anisotropic materials and polymeric composites used in soft robotic systems. in addition, potential applications for untethered soft robots are discussed based on the physicochemical properties of programmable anisotropic materials for the given external stimuli.”
🗊Wang, S., & Sun, Z.. (2023). Hydrogel and Machine Learning for Soft Robots’ Sensing and Signal Processing: A Review. Journal of Bionic Engineering
🗎“The soft robotics field is on the rise. the highly adaptive robots provide the opportunity to bridge the gap between machines and people. however, their elastomeric nature poses significant challenges to the perception, control, and signal processing. hydrogels and machine learning provide promising solutions to the problems above. this review aims to summarize this recent trend by first assessing the current hydrogel-based sensing and actuation methods applied to soft robots. we outlined the mechanisms of perception in response to various external stimuli. next, recent achievements of machine learning for soft robots’ sensing data processing and optimization are evaluated. here we list the strategies for implementing machine learning models from the perspective of applications. last, we discuss the challenges and future opportunities in perception data processing and soft robots’ high level tasks.”
🗊Wang, Y., Ma, X., Jiang, Y., Zang, W., Cao, P., Tian, M., … Zhang, L.. (2022). Dielectric elastomer actuators for artificial muscles: A comprehensive review of soft robot explorations. Resources Chemicals and Materials
🗎“Dielectric elastomer actuators (deas) artificial muscle is a typical interdisciplinary research category, which has developed by leaps and bounds in the past 20 years, showing great application prospects in various fields. upon external electrical stimulation, dielectric elastomers (des) display large deformation, high energy density and fast response, affording a promising material candidate for soft robotics. herein, the working mechanisms, commonly used materials as well as the concepts for improving the performance of dea materials are introduced. various dea driven soft robots, including soft grippers, bioinspired artificial arms, crawling/walking/underwater/flying/jumping soft robots and tunable lenses, are then described in detail. finally, the main challenges of dea driven soft robots are summarized, and some perspectives for promoting the practical application of deas are also proposed.”
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🗊Edwards, C.. (2012). Smart dust. Engineering and Technology
🗎“The paper gives an overview of the ‘smart dust’ – small, unobtrusive electronic sensors spread across the landscape. the sensors use the zigbee low-power wireless standard to send a message to relays mounted on street lamps, which then pass the data to a central computer. this surface-to-surface sensors can link up for the ultimate surveillance and control network of a smart city.”
🗊Warneke, B., Last, M., Liebowitz, B., & Pister, K. S. J.. (2001). Smart dust: communicating with a cubic-millimeter computer. Computer
🗎“The smart dust project is exploring whether an autonomous sensing, computing, and communication system can be packed into a cubic-millimeter mote to form the basis of integrated, massively distributed sensor networks. this project will facilitate innovative methods of interacting with the environment, providing more information from more places less intrusively.”
🗊O’Brien, D. C., Liu, J. J., Faulkner, G. E., Sivathasan, S., Yuan, W. W., Member, S. C., & Elston, S. J.. (2009). Design and implementation of optical wireless communications with optically powered smart dust motes. IEEE Journal on Selected Areas in Communications
🗊Rajesh, D., & Kiruba, D. G.. (2021). A probability based energy competent cluster based secured ch selection routing EC2SR protocol for smart dust. Peer-to-Peer Networking and Applications
🗎“Smart dust consists of several wireless mobile smart dust nodes which animatedly broadcast information amongst themselves without dependence of basestation. smart dust is more susceptible to diverse types of attacks and protect network because of its uniqueness of mobility in air and energetic in the environment. interruption means any irregular action that challenge to compromise reliability, privacy and accessibility of resources. a novel, dynamic energy efficient cluster based secure routing identifies these challenges while discovering exact routing and identifying malicious in smart dust node. design is structured as a dynamic hierarchy in which information is broadcasted among source to destination without any loss. to increase communication, more effectively dynamic hierarchy is reconfigured by inclusion of clustering techniques. cluster heads are selected based on residual energy and change in topology. proposed protocol is used for securing data and routing tactic will broadcasting. simulation of energy efficient cluster based secured routing protocol is carried out by ns2. this routing protocol provides enhanced energy efficiency, secured clustering, enlarges the lifetime of network, enhances deliverance ratio, delay and diminishes packet loss.”
Malin AJ, Eckel SP, Hu H, et al. Maternal Urinary Fluoride and Child Neurobehavior at Age 36 Months. JAMA Netw Open. 2024;7(5):e2411987. doi:10.1001/jamanetworkopen.2024.11987
Key Points
Question Is prenatal fluoride exposure associated with child neurobehavior in a US-based sample?
Findings In this cohort study of 229 pregnant women and their children, a 0.68 mg/L (ie, 1 IQR) increase in specific gravity–adjusted maternal urinary fluoride during pregnancy was associated with nearly double the odds of T scores for total child neurobehavioral problems being in the borderline clinical or clinical range.
Meaning These findings suggest that prenatal fluoride exposure may increase risk of neurobehavioral problems among children living in an optimally fluoridated area in the US.
Hu, C. J., Garcia, M. A., Nihart, A., Liu, R., Yin, L., Adolphi, N., Gallego, D. F., Kang, H., Campen, M. J., & Yu, X. (2024). Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis. Toxicological sciences : an official journal of the Society of Toxicology, kfae060. Advance online publication. doi.org/10.1093/toxsci/kfae060
Abstract
The ubiquitous existence of microplastics and nanoplastics raises concerns about their potential impact on the human reproductive system. Limited data exists on microplastics within the human reproductive system and their potential consequences on sperm quality. Our objectives were to quantify and characterize the prevalence and composition of microplastics within both canine and human testes and investigate potential associations with the sperm count, and weights of testis and epididymis. Using advanced sensitive Pyrolysis-Gas Chromatography/Mass Spectrometry (Py-GC/MS), we quantified 12 types of microplastics within 47 canine and 23 human testes. Data on reproductive organ weights, and sperm count in dogs were collected. Statistical analyses, including descriptive analysis, correlational analysis, and multivariate linear regression analyses were applied to investigate the association of microplastics with reproductive functions. Our study revealed the presence of microplastics in all canine and human testes, with significant inter-individual variability. Mean total microplastic levels were 122.63 µg/g in dogs and 328.44 µg/g in humans. Both humans and canines exhibit relatively similar proportions of the major polymer types, with PE being dominant. Furthermore, a negative correlation between specific polymers such as PVC and PET and the normalized weight of the testis was observed. These findings highlight the pervasive presence of microplastics in the male reproductive system in both canine and human testes, with potential consequences on male fertility.
Abstract: Healthcare 4.0 is a recent e-health paradigm associated with the concept of Industry 4.0. It provides approaches to achieving precision medicine that delivers healthcare services based on the patient’s characteristics. Moreover, Healthcare 4.0 enables telemedicine, including telesurgery, early predictions, and diagnosis of diseases. This represents an important paradigm for modern societies, especially with the current situation of pandemics. The release of the fifth-generation cellular system (5G), the current advances in wearable device manufacturing, and the recent technologies, e.g., artificial intelligence (AI), edge computing, and the Internet of Things (IoT), are the main drivers of evolutions of Healthcare 4.0 systems. To this end, this work considers introducing recent advances, trends, and requirements of the Internet of Medical Things (IoMT) and Healthcare 4.0 systems. The ultimate requirements of such networks in the era of 5G and next-generation networks are discussed. Moreover, the design challenges and current research directions of these networks. The key enabling technologies of such systems, including AI and distributed edge computing, are discussed.
URL: www.ncbi.nlm.nih.gov/pmc/articles/PMC10490658/
Sanger published the Birth Control Review from 1917 to 1929.
Cover of Birth Control Review July 1919 Captions: "How shall we change the law?", "Must She Always Plead in Vain? "You are a nurse - can you tell me? For the children's sake - help me!"
Sanger published the Birth Control Review from 1917 to 1929.
Advertisement for Margaret Sanger's book, "Woman and the New Race" Science & Invention, January 1922. Volume 9 Number 9, page 883. Image:Science and Invention Jan 1922
Excerpt from Lobaczewski, A. M. (2022). Political Ponerology: The Science of Evil, Psychopathy, and the Origins of Totalitarianism.
“I shall accept the denomination of pathocracy for a system of government thus created, wherein a small pathological minority takes control over a society of normal people. The name thus selected, above all, emphasizes the basic quality of the macrosocial psychopathological phenomenon, and differentiates it from the many possible social systems dominated by normal people’s structure, custom, and law. [...] Such a name sufficiently indicates the phenomenon’s basic quality and also emphasizes that the ideological cloak (or some other ideology which cloaked similar phenomena in the past) does not consti-tute its essence. .[...] In a pathocracy, all leadership positions, (down to village headman and community cooperative managers, not to mention the directors of police units, and special services police personnel, and activists in the pathocratic party) must be filled by individuals with corresponding psychological deviations, which are inherited as a rule. However, such people constitute a very small percentage of the population and this makes them more valuable to the pathocrats. Their intellectual level or professional skills cannot be taken into account, since people representing superior abilities are even harder to find. After such a system has lasted several years, one hundred percent of all the cases of essential psychopathy are involved in pathocratic activity; they are considered the most loyal, even though some of them were formerly involved on the other side in some way. Under such conditions, no area of social life can develop normally, whether in economics, culture, science, technology, administration, etc. Pathocracy progressively paralyzes everything. Normal people must develop a level of patience beyond the ken of anyone living in a normal man’s system just in order to explain what to do and how to do it to some obtuse mediocrity of a psychological deviant who has been placed in charge of some project that he cannot even understand, much less manage. This special kind of pedagogy – instructing deviants while avoiding their wrath – requires a great deal of time and effort, but it would otherwise not be possible to maintain tolerable living conditions and necessary achievements in the economic area or intellectual life of a society. Even with such efforts, pathocracy progressively intrudes everywhere and dulls everything. Those people who initially found the original ideology attractive eventually come to the realization that they are in fact dealing with something else that has taken its place under the old name. The disillusionment experienced by such former ideological adherents is bitter in the extreme. Thus, the pathological minority’s attempts to retain power will be threatened by the society of normal people, whose criticism keeps growing. Therefore, to mitigate the threat to their power, the pathocrats must employ any and all methods of terror and exterminatory policies against individuals known for their patriotic feelings and military training; other, specific “indoctrination” activities such as those we have presented are also utilized. Individuals lacking the natural feeling of being linked to normal society become irreplaceable in either of these activities. Again, the foreground of this type of activity is occupied by cases of essential psychopathy, followed by those with simi- lar anomalies, and finally by people alienated from the society in question as a result of racial or national differences. The phenomenon of pathocracy matures during this period: an extensive and active indoctrination system is built, with a suitably refurbished ideology constituting the vehicle or Trojan horse for the purpose of pathologizing the thought processes of individuals and society. The goal: Forcing human minds to incorporate pathological experiential methods and thoughtpatterns, and consequently accepting such rule is never openly admitted. This goal is conditioned by pathological egotism, and the possibility of accomplishing it strikes the pathocrats as not only indispensable, but feasible. Thousands of activists must therefore participate in this work. However, time and experience confirm what a psychologist may have long foreseen: the entire effort produces results so very limited that it is reminiscent of the labors of Sisyphus. It only results in producing a general stifling of intellectual development and deep-rooted protest against affront-mongering “hypocrisy”. The authors and executors of this program are incapable of understanding that the decisive factor making their work difficult is the fundamental nature of normal human beings – the majority. The entire system of force, terror, and forced indoctrination, or, rather, pathologization, thus proves effectively unfeasible, which causes the pathocrats no small measure of surprise. Re- ality places a question mark on their conviction that such methods can change people in such fundamental ways so that they can eventually recognize this pathocratic kind of govern- ment as a “normal state”. During the initial shock, the feeling of social links between normal people fade. After that has been survived, however, the overwhelming majority of people begin to manifest their own phenomenon of psychological immunization. Society simultaneously starts collecting practical knowledge on the subject of this new reality and its psychological properties. Normal people slowly learn to perceive the weak spots of such a system and utilize the possibilities of more expedient arrangement of their lives. They begin to give each other advice in these matters, thus slowly regenerating the feelings of social links and reciprocal trust. A new phenomenon occurs: separation between the pathocrats and the society of normal people. The latter have an advantage of talent, professional skills, and healthy common sense. They therefore hold certain very advantageous cards. The pathocracy finally realizes that it must find some modus vivendi or relations with the majority of society: 'After all, somebody’s got to do the work for us.' There are other needs and pressures felt by the pathocrats, especially from outside. The pathological face must be hidden from the world somehow, since recognition of the deviant rul- ership by world opinion would be a catastrophe. Ideological propaganda alone would then be an inadequate disguise. Primarily in the interests of the new elite and its expansionary plans, a pathocratic state must maintain commercial relations with the countries of normal man. The pathocratic state aims to achieve international recognition as a certain kind of political structure; and it fears recognition in terms of a true clinical diagnosis. [...] Any psychopathologist studying this phenomenon will be reminded of the dissimulative state or phase of a patient attempting to play the role of a normal person, hiding his pathological reality although he continues to be sick or abnormal. [...] . However, individuals with obvious pathological traits must be removed from certain areas of activity: namely, political posts with international exposure, where such personalities could betray the pathological contents of the phenomenon. Individuals with obvious pathological traits are also limited in their ability to exercise diplomatic functions or to become fully cognizant with the political situations of the countries of normal man. Therefore, the persons selected for such positions are chosen because they have thought-processes more similar to the world of normal people; in general, they are sufficiently connected to the pathological system to provide a guarantee of loyalty. An expert in various psychological anomalies can nevertheless discern the discreet deviations upon which such links are based. [...] Psychopaths are conscious of being different from normal people. That is why the “political system” inspired by their nature is able to conceal this awareness of being different. They wear a personal mask of sanity and know how to create a macrosocial mask of the same dissimulating nature. ” Lobaczewski, 2022, p. 193 et seq. [Lobaczewski, A. M. (2022). Political Ponerology: The Science of Evil, Psychopathy, and the Origins of Totalitarianism. Red Pill Press.]