Multilingual AI translation:

DDT (Dichlorodiphenyltrichloroethane): An experiment on the masses

DDT (dichloro-diphenyl-trichloroethane) was developed as the first of the modern synthetic insecticides in the 1940s. It was initially used with great effect to combat malaria, typhus, and the other insect-borne human diseases among both military and civilian populations (including “mass-spraying” on children – see video below). Toxicological studies demonstrate that DDT has numerous adverse effects (see references below).


Further References

Epstein, S. S.. (1972). Letters to the Editor. Science, 177(4047), 388–388.

Plain numerical DOI: 10.1126/science.177.4047.388
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Hawkey, A. B., Holloway, Z., Dean, C., Koburov, R., Slotkin, T. A., Seidler, F. J., & Levin, E. D.. (2021). Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact?. Neurotoxicology and Teratology, 87, 106985.

Plain numerical DOI: 10.1016/j.ntt.2021.106985
DOI URL
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Krzastek, S. C., Farhi, J., Gray, M., & Smith, R. P.. (2020). Impact of environmental toxin exposure on male fertility potential. Translational Andrology and Urology, 9(6), 2797–2813.

Plain numerical DOI: 10.21037/tau-20-685
DOI URL
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Russell, P. F.. (1972). DDT Toxicology. Science, 177(4047), 387–388.

Plain numerical DOI: 10.1126/science.177.4047.387
DOI URL
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Persson, E. C., Graubard, B. I., Evans, A. A., London, W. T., Weber, J.-P., LeBlanc, A., … McGlynn, K. A.. (2012). Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma. International Journal of Cancer, 131(9), 2078–2084.

Plain numerical DOI: 10.1002/ijc.27459
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Oliver, S. V., & Brooke, B. D.. (2013). The effect of larval nutritional deprivation on the life history and DDT resistance phenotype in laboratory strains of the malaria vector Anopheles arabiensis. Malaria Journal, 12(1), 44.

Plain numerical DOI: 10.1186/1475-2875-12-44
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Turusov, V., Rakitsky, V., & Tomatis, L.. (2002). Dichlorodiphenyltrichloroethane (DDT): ubiquity, persistence, and risks.. Environmental Health Perspectives, 110(2), 125–128.

Plain numerical DOI: 10.1289/ehp.02110125
DOI URL
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Booij, P., Holoubek, I., Klánová, J., Kohoutek, J., Dvorská, A., Magulová, K., … Čupr, P.. (2016). Current implications of past DDT indoor spraying in Oman. Science of The Total Environment, 550, 231–240.

Plain numerical DOI: 10.1016/j.scitotenv.2015.12.044
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Rosner, D., & Markowitz, G.. (2013). Persistent pollutants: A brief history of the discovery of the widespread toxicity of chlorinated hydrocarbons. Environmental Research, 120, 126–133.

Plain numerical DOI: 10.1016/j.envres.2012.08.011
DOI URL
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